If you notice iTunes not working smoothly on your Windows 10 PC/Laptop then first try to run the application with administrative privileges which allow it to bypass such restrictions and open up as usual. iTunes not working smoothly in windows 10
Select each of them and choose Uninstall and once you finish, restart your computer And try to run the latest iTunes setup which may resolve the issue.
Uninstall any old version of Apple programs at your Programs and Features page in your Control Panel: